Endocrine Abstracts

Hyperinsulinism has been shown to trigger sympathetic activity experimentally, however the clinical and epidemiologic data on the association of heart rate with hyperinsulinism and insulin resistance. This study was investigated the relationship between insulin resistance and exercise test parameters in unselected consecutive middle aged asymptomatic patients with type II diabetes.Ninety asymptomatic type II diabetics between the ages 36 and 60 without a...

In terms of mechanism by which thyroid diseases lead the endothelial dysfunction, several aspects have been taking into consideration. One potential factor may be variation in plasma asymmetric dimethylarginine (ADMA) levels. ADMA, which is derived from the catabolism of proteins containing methylated arginine residues, competitively inhibits NOS. The relationship between thyroid disease and variation in plasma ADMA levels is still a potential research area. The aim of this st...

Diabetes mellitus (DM) includes a group of carbohydrate metabolism disorders that is characterized by hyperglycemia and leads long-term macro- and microvascular complications. Also siblings of type 2 diabetic patients have increased relative risk of micro and macrovasculer outcome of DM even though their plasma glucose levels in normal range. Genetically determined hyperinsulinemia, insulin resistance and associated dyslipidemia have crucial role in the processes of vascular a...